The Mycobacterium tuberculosis ESAT-6 homologue in Listeria monocytogenes is dispensable for growth in vitro and in vivo.

نویسندگان

  • Sing Sing Way
  • Christopher B Wilson
چکیده

ESAT-6 is a virulence determinant in Mycobacterium tuberculosis and a member of a conserved group of proteins in a variety of other bacteria. A targeted deletion of the homologous gene in Listeria was generated, and in contrast to that observed for mycobacteria, this locus was not required for Listeria virulence.

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عنوان ژورنال:
  • Infection and immunity

دوره 73 9  شماره 

صفحات  -

تاریخ انتشار 2005